Come see us at ARVO 2026

Posters:

Sunday 5/3/2026 1:00p-2:45p
Ocular Safety of Suprachoroidal AAV.BMI1 in a Three-Month Minipig Study
Presenter: Andy Whitlock, PhD
Location: Exhibit Hall
Presentation Number: 0207
Session ID: 126

Tuesday 5/5/2026, 1:15p-3:00p
Retinal Resilience in Microgravity: RR-28 RNA-seq Demonstrates Safe, Stable Responses to AAV.BMI1
Presenter: Zhongyang Lu, MD PhD
Location: Exhibit Hall
Presentation Number: 0770
Session ID: 349

Tuesday 5/5/2026, 1:15p-3:00p
Non-GLP Assessment of Systemic BIodistribution, Viral Shedding, and Clinical Pathology Following Suprachoroidal AAV.BMI1 in Three-Month-Old Minipigs
Presenter: Shufeng Liu
Location: Exhibit Hall
Presentation Number: 0773
Session ID: 349

Tuesday 5/5/2026, 1:15p-3:00p
Panretinal Transgene Expression and Posterior Pole AAV8 Biodistribution Following Suprachoroidal Delivery with a Novel Device in Minipigs
Presenter: Hema Ramkumar, MD
Location: Exhibit Hall
Presentation Number: 0774
Session ID: 349

RECENT PUBLICATIONS:

1. Lu Z, Liu S, Morales MG, Whitlock A, Ramkumar R, Ramkumar HL. Retinal BMI1 Expression Preserves Photoreceptors in Sodium-Iodate-Induced Oxidative Stress Models. Int J Mol Sci. 2025 Jun 19;26(12):5907. 
2. Lu Z, Morales MG, Liu S, Ramkumar H. The Endogenous Expression of BMI1 in Adult Human Eyes. Special issue: Retinal Pigment Epithelial Cells in Age-Related Macular Degeneration. Cells 2024, 13 (19), 1672.

PAST PUBLICATIONS:

1. Zhongyang Lu, Andy Whitlock, Ram Ramkumar, Hema Ramkumar; Pharmacokinetics and Safety of  Suprachoroidal Delivery of AAV.BMI1 in C57/B6 Mice. Invest. Ophthalmol. Vis. Sci. 2024;65(7):201.

2. Zhongyang Lu, Sibley Bardales, Christina Kim, Gary Mansfield, Hema Ramkumar; Pharmacokinetic and Safety Analyses of rAAV8.BMI1 in C57BL/6 mice. Invest. Ophthalmol. Vis. Sci. 2023;64(8):1137.

3. Hema Ramkumar, Zhongyang Lu, Maria Gabriela Morales, Ram Ramkumar; The Endogenous Expression of BMI1 in Adult Human Eyes. Invest. Ophthalmol. Vis. Sci. 2024;65(7):207.

4. Sibley Bardales, Zhongyang Lu, Andy Whitlock, Hema Ramkumar; Potency Assay for AAV vector Encoding BMI1 Protein for the Treatment of Dry Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2023;64(8):1134